Hemophilia – A Blood Disease | Types Of Hemophilia | Full Guide

Hemophilia – A Blood Disease | Types Of Hemophilia | Full Guide

Hemophilia is an inherited bleeding disorder, major two types are Hemophilia A and Hemophilia B, and the third rarer form is Hemophilia C, know about its treatment.

What is Hemophilia?

Hemophilia is an inherited bleeding disorder due to which blooding clothing doesn’t occur normally and a person has low levels of clotting factor. It is a rare disease; there are three types of this disease, the major two types are Hemophilia A and Hemophilia B, and the third rarer form is Hemophilia C as stated by the N H F. It is a rare disorder in which the blood does not clot normally. It is noted that about 1 in 10,000 people born with this disease.

what is hemophilia

Types of Hemophilia

  1. Type A
  2. Type B
  3. Type C

types of hemophilia

Hemophilia A

It is common among people, and it is caused by a deficiency in factor VIII protein. It is inherited the disease and Caused by a spontaneous genetic mutation.

It has three stages:-

  • Mild
  • moderate
  • severe

We can distinguish between these types by counting the ratio of factor VIII clotting protein in the blood. The ratio is about 6-69 % in mild type and the ratio in moderate type is about 1-5% and the ratio is less than 1 % in severe one.

  • Mild  – The ratio is about 6-69 % in mild one. The person infected with Mild version of the disease  bleeds longer than others, internally and externally, but only after serious injury, trauma or surgery
  • Moderate  – The ratio in moderate one is about 1-5%. patients have more frequent bleeding after the regular intervals after injury, it can occur in the joints and muscles.
  • Severe  – the ratio is less than 1 % in severe one. The patient experiences frequent bleeding.

Hemophilia B

Caused by a deficiency in Factor IX clotting protein or Hemophilia B, it is inherited caused by a genetic mutation, it is a rare type of disease. This type of disease must be diagnosed at a specialized medical facility, it is called “Christmas disease”.

Hemophilia C

Hemophilia C is caused by a deficiency of factor XI. A patient infected with such with type C does not experience spontaneous bleeding. This type was first recognized in 1953. 1 in every 100,000 people experience type C.

Acquired Hemophilia

This type of Disease developed after birth (externally in the rare cases) is called “Acquired Hemophilia”. When the Immune system forms antibodies that attack factors VIII and IX.

You can Read: The Definitive Manual To Thalassemia

Symptoms

  • Blurred vision
  • Vomiting
  • Continuous bleeding from an injury
  • A severe headache

When these types of symptoms are seen, then one must visit doctors, one should take the right treatment.

Spontaneous bleeding can cause the following

  • Deep bruises
  • Blood in urine
  • Blood in the stool
  • Excessive bleeding
  • Bleeding gums
  • Pain in the joints
  • Tight joints
  • Nose bleeding.

Type  A and Type B are most common in males, because of genetic transmission. Type C affects males and females equally.

treatment of Hemophilia

Treatment

In many instances, a mild version of this disease isn’t diagnosed until an injury, surgery or tooth extraction leads to prolonged bleeding. Bleeding can occur anywhere in your children’s bodies. If the bleeding doesn’t stop, your kid may require a treatment of factor replacement therapy.  Prolonged bleeding can lead to serious health issues. That internal bleeding can harm your organs and tissues and could be life-threatening. As a consequence, blood clots can’t form properly in response to injury. Platelets are a kind of blood cell that will help form blood clots.

People with a gentle deficiency may bleed in the example of trauma. indications of hemophilia can be mild to severe, based on the degree of clotting factors you’ve got. They depend on how severe the condition is, but the main sign is prolonged bleeding. Patents must be treated at a specialized treatment center for the same.

Type A can be treated with a prescription hormone called desmopressin. It is given as an injection directly into the vein.

Type B can be treated by infusing blood with donor clotting factors called “Recombinant Clotting Factors.”

Type C can be treated by plasma infusing; it is used to stop profuse bleeding.

  • Avoid activities that may lead to injury.
  • Maintain a healthy body weight to limit the stress on joints.
  • An infant infected with this disease should have appropriate padding in his crib or playpen.
  • School-aged should avoid sports and activities that have a high risk of trauma.
  • Take Blood transfusion properly at the time.
  • Avoid medications that affect blood clotting.

Conclusion

Typically, individuals are born with a crucial protein called clotting factor, which aids the blood clot following an injury. There are several diverse mutations. The X chromosome comprises many genes that are not present on the Y chromosome. In the event the X chromosome that’s mostly inactivated carries the standard hemophilia gene, carrier women may experience bleeding or other symptoms linked to the disease.research has come a very long way. You might also want to get hold of a university or tertiary medical center locally, as these centers have a tendency to see more complex cases and have the newest technology and treatments.

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